Adenyl cyclase activity in human alveolar macrophages.
نویسندگان
چکیده
The inflammatory mediators PGE2, DC-PGI2 and histamine as well as the beta-adrenergic drugs isoprenaline and salbutamol increase intracellular cyclic AMP-concentrations whereas Platelet Activating Factor does not induce any change in adenyl cyclase activity of normal human alveolar macrophages. Functional H2-histaminergic and beta 2-adrenergic receptor-subtypes are coupled to macrophage adenyl cyclase.
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ورودعنوان ژورنال:
- Agents and actions. Supplements
دوره 31 شماره
صفحات -
تاریخ انتشار 1990